The effect of oral capsule of curcumin and vitamin E on the hot flashes and anxiety in postmenopausal women: A triple blind randomised controlled trial
Ataei-Almanghadim K, Farshbaf-Khalili A, Ostadrahimi AR, Shaseb E, Mirghafourvand M
Published in Complement Ther Med, Vol. 48, pp. 102267
Methodology
Triple-blind randomised trial in 93 postmenopausal women in Ahar, Iran: curcumin 500 mg, vitamin E 200 IU/day or placebo for 8 weeks; hot flash checklist at baseline, 4 and 8 weeks.
Key Findings
After 8 weeks the mean number of hot flashes was lower with vitamin E than placebo (adjusted mean difference -8.7, 95% CI -0.6 to -15.0, P = 0.029); the difference was not significant at 4 weeks (P = 0.052). No difference in anxiety, sexual function or overall menopausal symptoms.
Conclusions
Oral curcumin and vitamin E reduced hot flashes but not anxiety, sexual function or menopausal symptom scores.
Limitations
Small, single city, 8 weeks; the abstract does not give baseline hot flash counts, so the size of the effect is hard to judge.
Supplements Studied
Outcomes Measured
oral intake of curcumin and vitamin E significantly reduced hot flashes
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.