Effect of policosanol on lipid levels among patients with hypercholesterolemia or combined hyperlipidemia: a randomized controlled trial
Berthold HK, Unverdorben S, Degenhardt R, Bulitta M, Gouni-Berthold I
Published in JAMA
Methodology
Independent randomized double-blind placebo-controlled dose-ranging trial of policosanol 10 to 80 mg/day for 12 weeks in hypercholesterolemia
Key Findings
Policosanol had no effect on LDL cholesterol or any other lipid parameter at any dose compared with placebo
Conclusions
Policosanol did not lower cholesterol in this rigorous independent trial
Limitations
Single population studied; used non-Cuban policosanol preparation
Supplements Studied
Policosanol had no effect on LDL cholesterol or any other lipid parameter at any dose compared with placebo
Outcomes Measured
Policosanol had no effect on LDL cholesterol or any other lipid parameter at any dose compared with placebo
Policosanol had no effect on LDL cholesterol or any other lipid parameter at any dose compared with placebo
Related Health Concerns
Study Details
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