Bitter gourd (Momordica charantia L.) supplementation for twelve weeks improves biomarkers of glucose homeostasis in a prediabetic population
Mes JJ, van den Belt M, van der Haar S, Oosterink E, Luijendijk T
Published in Journal of Ethnopharmacology
Methodology
Two randomized controlled studies: a 4-week cross-over trial of freeze-dried bitter gourd juice (2.4 g/day) and a 12-week parallel trial of freeze-dried whole fruit (3.6 g/day) versus cucumber-based control.
Key Findings
No significant between-group differences in the 4-week cross-over study; the 12-week parallel trial showed significant reductions in fasting plasma glucose (p = 0.014).
Conclusions
Longer supplementation with whole-fruit bitter gourd improved glucose homeostasis markers in prediabetic adults.
Limitations
Small samples, two differing preparations, short follow-up.
Supplements Studied
In Study 2, we observed significant reductions of FPG (p = 0.014)
Outcomes Measured
In Study 2, we observed significant reductions of FPG (p = 0.014)
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.