Clinical evidence of the effects of carnitine supplementation on body weight, glycemic control and serum lipids in women with polycystic ovary syndrome: a systematic review and meta-analysis
Liao D, Liu X, Yuan X, Feng P, Ouyang Z, Liu Y, Li C
Published in Gynecological Endocrinology
Methodology
Meta-analysis of 6 randomized controlled trials of carnitine supplementation in women with PCOS
Key Findings
Carnitine significantly decreased body weight, BMI, hip and waist circumference, total cholesterol, LDL-C and triglycerides; no significant change in glucose homeostasis parameters.
Conclusions
Carnitine supplementation had beneficial effects on weight loss and lipid profiles in women with PCOS, though larger well-designed RCTs are required.
Limitations
Limited to women with PCOS; small number of included trials; heterogeneity in dose and duration.
Supplements Studied
carnitine supplements significantly decreased ... body weight, body mass index, hip circumference, and waist circumference
Outcomes Measured
carnitine supplements significantly decreased total cholesterol, low-density lipoprotein-cholesterol, triglycerides, body weight, body mass index, hip circumference, and waist circumference
Study Details
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