Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Unknown authors
Published in Nutrients
Key Findings
73 patients randomised; active combination improved pain score, B12 levels, vibration perception threshold and sural nerve conduction versus placebo.
Conclusions
A multi-nutrient combination improved neuropathic symptoms over 6 months in diabetic neuropathy.
Supplements Studied
In the active group, there was a large improvement of pain (PS from 20.9 to 13.9, p < 0.001).
73 patients randomised; active combination improved pain score, B12 levels, vibration perception threshold and sural nerve conduction versus placebo.
73 patients randomised; active combination improved pain score, B12 levels, vibration perception threshold and sural nerve conduction versus placebo.
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Study Details
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