Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study
Brien S, Lewith G, Walker AF, Middleton R, Prescott P, Bundy R
Published in QJM
Abstract
Randomized placebo-controlled pilot trial of adjunctive bromelain in moderate-to-severe knee osteoarthritis.
Key Findings
Bromelain was no better than placebo for WOMAC pain, stiffness or function in moderate-to-severe knee osteoarthritis, and dropout was high in both arms.
Conclusions
This well-conducted pilot found no benefit of bromelain in more severe knee osteoarthritis.
Limitations
Pilot size, high attrition, single 12-week course.
Supplements Studied
Bromelain was no better than placebo for WOMAC pain, stiffness or function in moderate-to-severe knee osteoarthritis, and dropout was high in both arms.
Outcomes Measured
Bromelain was no better than placebo for WOMAC pain, stiffness or function in moderate-to-severe knee osteoarthritis, and dropout was high in both arms.
Related Health Concerns
Study Details
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