To evaluate the effect of adding licorice to the standard treatment regimen of Helicobacter pylori
Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S
Published in Brazilian Journal of Infectious Diseases
Methodology
Randomised controlled clinical trial in 120 dyspeptic patients with positive rapid urease test, comparing clarithromycin-based triple therapy alone versus triple therapy plus licorice for two weeks, with eradication assessed six weeks after therapy
Key Findings
Adding licorice to standard triple therapy raised eradication response from about 62.5% to 83.3%.
Conclusions
Licorice may work as an adjunct to conventional eradication therapy rather than as a stand-alone treatment.
Limitations
Open-label; single-centre; no placebo arm; modest sample.
Supplements Studied
Response to treatment was 83.3% and 62
Outcomes Measured
The aim of this study was to evaluate the effect of licorice in H. pylori eradication in patients suffering from dyspepsia either with peptic ulcer disease (PUD) or non-ulcer dyspepsia (NUD)
Study Details
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Disclosures
Funding
Not reported
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