Vitamin C supplementation and luteal phase progesterone in women with luteal phase defect: a randomized trial
Henmi H, Endo T, Kitajima Y, Manase K, Hata H, Kudo R
Published in Fertility and Sterility
Methodology
Randomized controlled trial of 750 mg daily vitamin C versus no treatment in infertile women with luteal phase defect, measuring serum progesterone.
Key Findings
Serum progesterone rose significantly in the vitamin C group compared with untreated controls, with a higher pregnancy rate.
Conclusions
Vitamin C may modestly support luteal progesterone production.
Limitations
No placebo control; single small trial.
Supplements Studied
Serum progesterone rose significantly in the vitamin C group compared with untreated controls
Outcomes Measured
Serum progesterone rose significantly in the vitamin C group compared with untreated controls
Serum progesterone rose significantly in the vitamin C group compared with untreated controls, with a higher pregnancy rate
Study Details
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