rct
    2012
    High Quality

    Antioxidant therapy does not reduce pain in patients with chronic pancreatitis: the ANTICIPATE study

    Siriwardena AK, Mason JM, Sheen AJ

    Published in Gastroenterology

    Methodology

    Randomised double-blind placebo-controlled trial of a combined antioxidant preparation over 6 months in painful chronic pancreatitis.

    Key Findings

    There was no difference in pain scores, quality of life or analgesic use between antioxidant and placebo groups despite increased antioxidant levels.

    Conclusions

    Antioxidant therapy failed to relieve pain in a well-designed trial.

    Limitations

    Single-centre; modest sample size.

    Supplements Studied

    Selenium
    Mineral

    There was no difference in pain scores, quality of life or analgesic use between antioxidant and placebo groups.

    Related Health Concerns

    Chronic Pancreatitis

    Study Details

    Year:2012
    Sample Size:70
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

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