Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans
Abdou AM, Higashiguchi S, Horie K, Kim M, Hatta H, Yokogoshi H
Published in BioFactors
Key Findings
After 60 minutes of administration, GABA significantly increased alpha waves and decreased beta waves compared with water or L-theanine; salivary IgA was preserved during an acrophobic stressor.
Conclusions
Oral GABA may induce relaxation and reduce anxiety-related immune suppression.
Limitations
Very small samples (13 and 8 subjects), industry-affiliated authors, surrogate EEG endpoints.
Supplements Studied
The effect of orally administrated gamma-aminobutyric acid (GABA) on relaxation and immunity during stress has been investigated in humans.
After 60 minutes of administration, GABA significantly increased alpha waves and decreased beta waves compared with water or L-theanine; salivary IgA was preserved during an acrophobic stressor.
Outcomes Measured
After 60 minutes of administration, GABA significantly increases alpha waves and decreases beta waves compared to water or L-theanine.
Study Details
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