Betaine hydrochloride restores gastric acidity and downstream protein digestion in hypochlorhydria
Yago MR, Frymoyer AR, Smelick GS, Frymoyer A, Budha NR, Dickmann LJ
Published in Molecular Pharmaceutics
Methodology
Controlled crossover study measuring gastric pH after betaine hydrochloride administration in volunteers with drug-induced hypochlorhydria.
Key Findings
Betaine hydrochloride rapidly lowered gastric pH below 3 for a median of 73 minutes, temporarily restoring an acidic digestive environment.
Conclusions
Betaine HCl can restore the gastric acidity that primes pancreatic enzyme activity.
Limitations
Small healthy-volunteer study; no clinical digestion endpoints.
Supplements Studied
Betaine hydrochloride rapidly lowered gastric pH below 3 for a median of 73 minutes
Outcomes Measured
Betaine hydrochloride rapidly lowered gastric pH below 3 for a median of 73 minutes, temporarily restoring an acidic digestive environment
Study Details
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