Effects of supplementation with milk protein on glycemic parameters: a GRADE-assessed systematic review and dose-response meta-analysis
Mohammadi S, Asbaghi O, Dolatshahi S, Omran HS, Amirani N
Published in Nutrition Journal
Methodology
Dose-response meta-analysis of 36 randomized controlled trials (1851 participants) of milk protein (including casein) supplementation on glycaemic markers
Key Findings
Milk protein reduced fasting blood glucose by 1.83 mg/dL, fasting insulin by 1.06 uU/mL and HOMA-IR by 0.27, with no change in HbA1c.
Conclusions
Milk protein supplementation produces small improvements in fasting glucose and insulin resistance markers but does not change longer-term glycaemic control.
Limitations
Effect sizes are clinically marginal; pooled whey and casein together; GRADE certainty limited by heterogeneity.
Supplements Studied
Supplementation with MP effectively reduced levels of fasting blood glucose (WMD: -1.83 mg/dL) ... while making no remarkable changes in serum hemoglobin A1c (HbA1c) values.
Outcomes Measured
Supplementation with MP effectively reduced levels of fasting blood glucose (WMD: -1.83 mg/dL) while making no remarkable changes in serum hemoglobin A1c (HbA1c) values.
Related Health Concerns
Study Details
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Disclosures
Funding
Not specified
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