The efficacy of glucomannan supplementation in overweight and obesity: a systematic review and meta-analysis of randomized clinical trials
Onakpoya I, Posadzki P, Ernst E
Published in Journal of the American College of Nutrition
Methodology
Systematic review and random-effects meta-analysis of 8 randomized controlled trials in overweight/obese participants
Key Findings
No statistically significant difference in weight loss between glucomannan and placebo (MD -0.22 kg; 95% CI -0.62 to 0.19; I2 = 65%). Adverse events included abdominal discomfort, diarrhea and constipation.
Conclusions
Available RCTs do not show that glucomannan intake generates statistically significant weight loss.
Limitations
Variable reporting quality of included trials; moderate heterogeneity.
Outcomes Measured
The evidence from available RCTs does not show that glucomannan intake generates statistically significant weight loss
Study Details
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