The genus Rumex: review of traditional uses, phytochemistry and pharmacology
Vasas A, Orban-Gyapai O, Hohmann J
Published in Journal of Ethnopharmacology
Methodology
Systematic review of ethnomedical uses, isolated compounds and pharmacological studies of Rumex species including Rumex crispus (yellow dock).
Key Findings
Rumex species contain anthraquinones (emodin, chrysophanol), flavonoids and tannins with laxative, antimicrobial, antioxidant and anti-inflammatory activity in preclinical models; no controlled human trials were identified.
Conclusions
Yellow dock has a plausible anthraquinone-based laxative mechanism, but clinical efficacy and safety in humans are unstudied.
Limitations
No clinical trials available; oxalate and anthraquinone safety concerns not quantified.
Supplements Studied
Rumex species contain anthraquinones with laxative, antimicrobial and antioxidant activity in preclinical models; no controlled human trials were identified.
Rumex species contain anthraquinones (emodin, chrysophanol), flavonoids and tannins with laxative, antimicrobial, antioxidant and anti-inflammatory activity in preclinical models; no controlled human trials were identified.
Outcomes Measured
Rumex species contain flavonoids and tannins with antioxidant activity in preclinical models.
Related Health Concerns
Study Details
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