Dietary Interventions in the Management of Fibromyalgia: A Systematic Review and Best-Evidence Synthesis
Lowry E
Published in Nutrients
Methodology
Systematic review and best-evidence synthesis of dietary and nutritional interventions in fibromyalgia syndrome, including 18 randomised controlled trials and 4 cohort studies covering 17 distinct interventions.
Key Findings
This systematic review of dietary interventions for fibromyalgia included 22 studies (18 randomised trials and 4 cohort studies) covering 17 different nutritional interventions. Significant improvements in reported pain were seen with a vegan diet and with low FODMAP diets, and with supplementation using Chlorella green algae, coenzyme Q10, acetyl-L-carnitine, or vitamin C combined with vitamin E. However, the authors judged interpretation to be limited by poor study design, wide heterogeneity, small samples and a high degree of bias, concluding there is insufficient evidence to recommend any single nutritional approach.
Conclusions
Insufficient evidence to recommend any one nutritional intervention.
Limitations
Included studies were small, heterogeneous and at high risk of bias, and dietary trials cannot be blinded, so placebo and expectancy effects are hard to exclude; no single intervention has enough evidence behind it.
Related Health Concerns
Study Details
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