Administration of a probiotic with peanut oral immunotherapy: a randomized trial
Tang ML, Ponsonby AL, Orsini F, Tey D, Robinson M, Su EL, Donath S
Published in Journal of Allergy and Clinical Immunology
Key Findings
Combined Lactobacillus rhamnosus plus peanut oral immunotherapy induced possible sustained unresponsiveness in 82.1% versus 3.6% on placebo.
Conclusions
Probiotic-adjuvanted immunotherapy is promising but the probiotic contribution cannot be isolated.
Limitations
No OIT-alone arm; small single-centre trial.
Supplements Studied
Lactobacillus rhamnosus combined with oral immunotherapy was associated with sustained unresponsiveness to peanut.
Combined Lactobacillus rhamnosus plus peanut oral immunotherapy induced possible sustained unresponsiveness in 82.1% versus 3.6% on placebo.
Outcomes Measured
Probiotic-adjuvanted immunotherapy shifted peanut-specific immune responses toward tolerance.
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.