Digestive enzyme supplementation for functional gastrointestinal symptoms: a randomized double-blind trial
Money ME, Walkowiak J, Virgilio C, Talley NJ
Published in Frontline Gastroenterology
Methodology
Randomized double-blind placebo-controlled crossover trial of a pancrelipase preparation before high-fat meals in patients with functional postprandial symptoms.
Key Findings
Pancrelipase reduced post-meal bloating, gas and cramping compared with placebo.
Conclusions
Enzyme supplementation can relieve fat-related digestive symptoms without diagnosed insufficiency.
Limitations
Small crossover study; single high-fat meal challenge.
Supplements Studied
Pancrelipase reduced post-meal bloating, gas and cramping compared with placebo
Outcomes Measured
Pancrelipase reduced post-meal bloating, gas and cramping compared with placebo
Study Details
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