The effect of lutein on eye and extra-eye health
Buscemi S, Corleo D, Di Pace F, Petroni ML, Satriano A, Marchesini G
Published in Nutrients
Abstract
Comprehensive review of lutein benefits beyond eye health. Dosages of 10-20mg daily shown to improve macular pigment density, contrast sensitivity, glare recovery, and visual processing speed. Also demonstrates cognitive benefits, skin photoprotection, and cardiovascular effects. Excellent safety profile with no adverse effects at nutritional doses. Synergistic effects with zeaxanthin and omega-3 fatty acids.
Methodology
Narrative review of observational studies and clinical trials of dietary and supplemental lutein.
Key Findings
Lutein 10-20 mg/day raises macular pigment optical density and improves contrast sensitivity, glare recovery and visual processing speed; observational and interventional data also suggest benefits for cognitive performance and markers of inflammation, though extra-eye evidence is weaker than ocular evidence.
Conclusions
Lutein has consistent supportive evidence for eye health at 10-20 mg/day; claims for extra-eye benefits remain preliminary.
Limitations
Narrative review with no systematic search or risk-of-bias assessment; heterogeneous doses, formulations and outcome measures across the included literature.
Supplements Studied
Lutein accumulates in the macula and skin and has documented roles beyond ocular tissue.
Outcomes Measured
Comprehensive review showing 10-20mg lutein daily improves macular pigment density, contrast sensitivity, glare recovery, and visual processing speed. Also demonstrates cognitive, skin, and cardiovascular benefits.
Study Details
Access Study
Disclosures
Funding
No external funding reported (University of Palermo authors).
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.