rct
    2011

    Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction

    Cormio L, De Siati M, Lorusso F, Selvaggio O, Mirabella L, Sanguedolce F, Carrieri G

    Published in Urology

    Methodology

    Single-blind study in men with mild erectile dysfunction receiving one month of placebo followed by one month of L-citrulline 1.5 g/day.

    Key Findings

    Erection hardness score improved from mild ED to normal in 50% of men on L-citrulline versus 8.3% on placebo, with increased intercourse frequency.

    Conclusions

    L-citrulline improved erection hardness in mild erectile dysfunction, though less effectively than PDE5 inhibitors.

    Limitations

    Small single-blind study, no parallel randomization, short duration, subjective primary endpoint.

    Supplements Studied

    L-Citrulline
    Amino Acid

    Erection hardness score improved to normal in 50% of men on L-citrulline versus 8.3% on placebo.

    Outcomes Measured

    Erection hardness score improved to normal in 50% of men taking L-citrulline versus 8.3% on placebo.

    Erection hardness improved from mild dysfunction to normal in 50% of citrulline patients versus 8.3% on placebo

    Related Health Concerns

    Study Details

    Year:2011
    Sample Size:24
    Duration:8 weeks
    Quality Score:5/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.