cohort
    2008
    High Quality

    Long-Term Effect of Magnesium Consumption on the Risk of Symptomatic Gallstone Disease Among Men

    Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL

    Published in The American Journal of Gastroenterology

    Methodology

    Prospective cohort (Health Professionals Follow-up Study) using validated food-frequency questionnaires to relate magnesium intake to incident symptomatic gallstone disease

    Key Findings

    Men in the highest quintile of magnesium intake had about 28 percent lower risk of symptomatic gallstone disease than the lowest quintile

    Conclusions

    Higher long-term magnesium consumption is associated with reduced risk of symptomatic gallstone disease in men

    Limitations

    Observational; all-male cohort; self-reported dietary intake

    Supplements Studied

    Magnesium
    Mineral

    Increasing consumption of magnesium appears to decrease the risk of symptomatic gallstones in men, although the underlying mechanisms remain unclear.

    Related Health Concerns

    Study Details

    Year:2008
    Sample Size:42,705
    Quality Score:7/10

    Disclosures

    Funding

    National Institutes of Health

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.