rct
    2012
    High Quality

    Fish oil and postoperative atrial fibrillation: the OPERA randomized trial

    Mozaffarian D, Marchioli R, Macchia A

    Published in JAMA

    Methodology

    Multinational double-blind placebo-controlled RCT of perioperative n-3 PUFA in patients undergoing cardiac surgery.

    Key Findings

    Perioperative fish oil did not reduce postoperative atrial fibrillation (30.7% vs 30.0%, OR 0.96).

    Conclusions

    High-dose perioperative omega-3 does not prevent post-surgical atrial fibrillation.

    Limitations

    Surgical population; short exposure; may not generalise to chronic arrhythmia prevention.

    Supplements Studied

    High-dose perioperative omega-3 does not prevent post-surgical atrial fibrillation.

    Outcomes Measured

    Heart Health Support

    Perioperative fish oil did not reduce postoperative atrial fibrillation.

    Related Health Concerns

    Arrhythmia

    Study Details

    Year:2012
    Sample Size:1,516
    Quality Score:9/10

    Access Study

    View on DOIView on PubMedOriginal Source

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