Vitamin D and hematopoietic and mesenchymal stem cell function: a review of clinical evidence
Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM
Published in Cell Reports
Methodology
Mechanistic and translational studies of vitamin D receptor signalling in haematopoietic stem and progenitor cell expansion.
Key Findings
Vitamin D signalling amplified haematopoietic stem and progenitor cell production, an effect conserved from zebrafish to human cells.
Conclusions
Vitamin D status influences stem cell pool maintenance.
Limitations
Preclinical; no human supplementation outcome trials.
Supplements Studied
Vitamin D signalling amplified haematopoietic stem and progenitor cell production
Outcomes Measured
Vitamin D signalling amplified haematopoietic stem and progenitor cell production, an effect conserved from zebrafish to human cells
Study Details
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