Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis
Ma L, Dou HL, Wu YQ, Huang YM, Huang YB, Xu XR, Zou ZY, Lin XM
Published in British Journal of Nutrition
Methodology
Systematic review and meta-analysis of prospective cohort and case-control studies of dietary lutein and zeaxanthin intake and AMD risk.
Key Findings
Higher dietary lutein and zeaxanthin intake was not associated with reduced risk of early AMD, but was associated with a 26% lower risk of late AMD and neovascular AMD.
Conclusions
Dietary lutein and zeaxanthin appear protective against late-stage but not early age-related macular degeneration.
Limitations
Observational data subject to confounding and dietary measurement error; no randomised evidence for prevention.
Supplements Studied
Higher dietary lutein and zeaxanthin intake was associated with a 26% lower risk of late age-related macular degeneration.
Higher dietary lutein and zeaxanthin intake was associated with a 26% lower risk of late age-related macular degeneration but not early AMD.
Outcomes Measured
Higher dietary lutein and zeaxanthin intake was associated with a 26% lower risk of late AMD.
Related Health Concerns
Study Details
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