observational
    2023
    High Quality

    Taurine deficiency as a driver of aging

    Singh P, Gollapalli K, Mangiola S

    Published in Science

    Methodology

    Cross-species study of circulating taurine with age plus supplementation experiments in mice, monkeys and worms

    Key Findings

    Circulating taurine declined with age across species; taurine supplementation increased median lifespan in mice and improved health markers

    Conclusions

    Taurine deficiency may be a driver of aging in animals; human causal data are lacking

    Limitations

    Animal work; human data limited to observational associations

    Supplements Studied

    Taurine
    Amino Acid

    Circulating taurine declines with age and supplementation increased median lifespan in mice

    Study Details

    Year:2023
    Quality Score:7/10

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