Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men
Tang JE, Moore DR, Kujbida GW, Tarnopolsky MA, Phillips SM
Published in Journal of Applied Physiology
Methodology
Randomised crossover trial with stable isotope infusion measuring mixed muscle protein synthesis after ingestion of whey hydrolysate, casein or soy isolate.
Key Findings
Whey hydrolysate stimulated muscle protein synthesis significantly more than casein at rest and more than both casein and soy after resistance exercise.
Conclusions
Rapidly digested, leucine-rich whey protein is a superior acute stimulus for muscle protein synthesis than casein or soy.
Limitations
Acute mechanistic study in young men only; no long-term hypertrophy outcomes.
Supplements Studied
Whey hydrolysate stimulated muscle protein synthesis significantly more than casein at rest and more than casein and soy after resistance exercise.
Outcomes Measured
Whey hydrolysate stimulated mixed muscle protein synthesis more than casein at rest and more than casein and soy after resistance exercise.
Study Details
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