rct
    2005
    High Quality

    Grape seed extract and cognitive or oxidative outcomes in healthy adults: a randomised placebo-controlled trial with null primary findings

    Ward NC, Croft KD, Puddey IB, Hodgson JM

    Published in Journal of Hypertension

    Methodology

    Randomised placebo-controlled crossover trial of grape seed polyphenols in treated hypertensive adults measuring blood pressure and oxidative stress markers

    Key Findings

    Grape seed polyphenols did not significantly reduce blood pressure or markers of oxidative stress compared with placebo in this population.

    Conclusions

    Blood pressure benefits of grape seed extract are not consistent across all populations.

    Limitations

    Small crossover sample in already-treated hypertensives.

    Supplements Studied

    Grape seed polyphenols did not significantly lower blood pressure or oxidative stress markers compared with placebo.

    Related Health Concerns

    Study Details

    Year:2005
    Sample Size:36
    Duration:6 weeks
    Quality Score:7/10

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