rct
    2014
    High Quality

    A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia

    Unknown authors

    Published in Journal of the American Academy of Dermatology

    Key Findings

    Dutasteride increased hair count and width dose-dependently versus placebo and outperformed finasteride, with comparable adverse event rates over 24 weeks.

    Conclusions

    Greater systemic DHT suppression produces greater hair regrowth, establishing a dose-response for 5-alpha-reductase inhibition.

    Outcomes Measured

    DHT Reduction
    Primary

    Dutasteride increased hair growth and restoration in a dose-dependent fashion.

    DHT Balance
    Primary

    Dutasteride increased hair growth and restoration in a dose-dependent fashion.

    Study Details

    Year:2014
    Quality Score:8/10

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    View on DOIView on PubMedOriginal Source

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