crossover
    2015

    A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles

    Unknown authors

    Published in Scientific Reports

    Key Findings

    A single 2,000 FU dose of nattokinase lowered fibrinogen, factor VII and factor VIII and enhanced fibrinolytic activity over 8 hours in healthy men.

    Conclusions

    Acute nattokinase dosing measurably shifts coagulation and fibrinolysis parameters.

    Limitations

    Very small, healthy young male sample; single acute dose only.

    Supplements Studied

    A single-dose of 2,000 FU nattokinase potentiated thrombolysis and anti-coagulation profiles in healthy male subjects.

    Outcomes Measured

    Fibrinogen Reduction
    Primary

    A single-dose of 2,000 FU nattokinase significantly decreased fibrinogen, factor VII and factor VIII levels within 8 hours of administration.

    Study Details

    Year:2015
    Sample Size:12
    Duration:1 weeks
    Quality Score:5/10

    Access Study

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