Effects of Marine n-3 Polyunsaturated Fatty Acids on Heart Rate Variability and Heart Rate in Patients on Chronic Dialysis: A Randomized Controlled Trial
Rantanen JM, Riahi S, Johansen MB, Schmidt EB, Christensen JH
Published in Nutrients
Key Findings
Marine n-3 PUFA did not change the primary endpoint SDNN, but other HRV indices increased and heart rate fell by about 2.5 beats per minute.
Conclusions
Omega-3 failed on the primary HRV endpoint while showing signs of increased vagal modulation.
Limitations
Primary endpoint negative; dialysis population limits generalisability; modest sample.
Supplements Studied
Marine n-3 PUFA did not change the primary endpoint SDNN (SD of all RR-intervals) reflecting overall HRV
Outcomes Measured
Marine n-3 PUFA did not change the primary endpoint SDNN (SD of all RR-intervals) reflecting overall HRV, but other HRV indices increased and the mean RR-interval increased significantly
Study Details
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