Selenium supplementation and cellular immune response: a randomized placebo-controlled trial
Broome CS, McArdle F, Kyle JA, Andrews F, Lowe NM, Hart CA, Arthur JR, Jackson MJ
Published in American Journal of Clinical Nutrition
Methodology
Randomized placebo-controlled trial of selenium 50 or 100 mcg/day in adults with marginal selenium status, challenged with live attenuated poliovirus.
Key Findings
Selenium supplementation increased T-cell proliferation and accelerated poliovirus clearance compared with placebo.
Conclusions
Correcting marginal selenium status improves cellular immunity.
Limitations
Small sample; marginal-status population only.
Supplements Studied
Selenium supplementation increased T-cell proliferation and accelerated poliovirus clearance compared with placebo
Outcomes Measured
Selenium supplementation increased T-cell proliferation and accelerated poliovirus clearance compared with placebo
Study Details
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