rct
    2023
    High Quality

    The effects of creatine supplementation on cognitive performance — a randomised controlled study

    Sandkühler JF, Kersting X, Faust A, Königs EK, Altman G, Ettinger U, Lux S, Philipsen A, Müller H, Brauner J

    Published in BMC Medicine

    Methodology

    Randomized, double-blind, placebo-controlled crossover trial of creatine 5 g/day for 6 weeks in healthy adults, assessing Raven's Advanced Progressive Matrices and backward digit span.

    Key Findings

    Creatine produced no statistically significant improvement in the primary cognitive outcomes compared with placebo in healthy, mostly omnivorous adults.

    Conclusions

    Six weeks of creatine supplementation did not improve cognitive performance in healthy adults.

    Limitations

    Predominantly omnivorous, well-rested participants may have had little headroom for benefit; standard rather than high-dose protocol.

    Supplements Studied

    Creatine produced no statistically significant improvement in the primary cognitive outcomes compared with placebo.

    Outcomes Measured

    Creatine produced no statistically significant improvement in the primary cognitive outcomes compared with placebo.

    Related Health Concerns

    Study Details

    Year:2023
    Sample Size:123
    Duration:6 weeks
    Quality Score:9/10

    Disclosures

    Funding

    Academic (university-funded, no industry support)

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.