rct
    2011

    Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study

    Debbi EM, Agar G, Fichman G

    Published in BMC Complementary and Alternative Medicine

    Key Findings

    MSM 3.4 g/day for 12 weeks produced small but statistically significant improvements in WOMAC pain and function versus placebo, of uncertain clinical importance.

    Conclusions

    Modest symptomatic benefit at best.

    Limitations

    Small sample, short duration.

    Supplements Studied

    MSM
    Compound

    MSM 3.4 g/day improved WOMAC pain and function versus placebo, though the effect size was small.

    Sulfur
    Mineral

    MSM 3.4 g/day for 12 weeks produced small but statistically significant improvements in WOMAC pain and function versus placebo, of uncertain clinical importance.

    Outcomes Measured

    Joint Comfort

    MSM produced statistically significant but small reductions in WOMAC pain.

    Related Health Concerns

    Osteoarthritis
    Joint Pain
    Shoulder Pain

    Study Details

    Year:2011
    Sample Size:50
    Duration:12 weeks
    Quality Score:6/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.