rct
    2019
    High Quality

    Randomized trial of L-serine in patients with hereditary sensory and autonomic neuropathy type 1

    Fridman V, Suriyanarayanan S, Novak P

    Published in Neurology

    Key Findings

    L-serine 400 mg/kg/day for one year improved the CMT Neuropathy Score compared with placebo and lowered neurotoxic deoxysphingolipids.

    Conclusions

    Disease-specific benefit in a rare genetic neuropathy.

    Limitations

    Very small orphan population.

    Supplements Studied

    L-Serine
    Amino Acid

    L-serine 400 mg/kg/day improved the CMT Neuropathy Score versus placebo and lowered neurotoxic deoxysphingolipids.

    Outcomes Measured

    Nerve Health

    L-serine improved neuropathy scores and reduced neurotoxic deoxysphingolipids in HSAN1.

    Study Details

    Year:2019
    Sample Size:18
    Duration:52 weeks
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.