systematic_review
    2020

    Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement

    Holecek M

    Published in Nutrients

    Key Findings

    Reviews histidine roles in carnosine and histamine synthesis, antioxidant activity, and the mixed clinical evidence for supplementation.

    Conclusions

    Supplementation benefits remain limited to specific deficiency states.

    Limitations

    Narrative review without pooled analysis.

    Supplements Studied

    L-Histidine
    Amino Acid

    Histidine is required for carnosine and histamine synthesis and shows antioxidant activity, but clinical supplementation evidence remains limited.

    Study Details

    Year:2020
    Quality Score:6/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.