rct
    2013
    High Quality

    Histidine supplementation improves insulin resistance through suppressed inflammation in obese women with the metabolic syndrome: a randomised controlled trial

    Feng RN, Niu YC, Sun XW

    Published in Diabetologia

    Key Findings

    Histidine 4 g/day for 12 weeks reduced HOMA-IR, fasting insulin, BMI and inflammatory markers in obese women with metabolic syndrome.

    Conclusions

    Signal for an anti-inflammatory metabolic effect in this population.

    Limitations

    Single centre, women only, not replicated.

    Supplements Studied

    L-Histidine
    Amino Acid

    Histidine supplementation reduced HOMA-IR, fasting insulin and inflammatory markers in obese women with metabolic syndrome.

    Outcomes Measured

    Blood Sugar Balance

    Fasting insulin and HOMA-IR fell significantly with histidine supplementation versus placebo.

    Related Health Concerns

    Metabolic Syndrome
    Obesity
    Insulin Resistance

    Study Details

    Year:2013
    Sample Size:100
    Duration:12 weeks
    Quality Score:7/10

    Access Study

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    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.