The effects of astaxanthin supplementation on liver enzyme levels
Arefpour H, Rasaei N, Amini MR, Salavatizadeh M, Hashemi M, Makhtoomi M, Hajiaqaei M, Gholizadeh M, Askarpour M, Hekmatdoost A
Published in International Journal for Vitamin and Nutrition Research
Methodology
Meta-analysis of 5 RCTs (6-12 mg/day, 4-48 weeks) of astaxanthin on ALT, AST, GGT and ALP
Key Findings
ALT increased slightly versus control (WMD +1.92 U/L, p=0.03); AST, GGT and ALP showed no significant change.
Conclusions
Astaxanthin did not improve liver enzymes and was associated with a small increase in ALT.
Limitations
Only five small trials; clinical relevance of a ~2 U/L ALT change is unclear.
Supplements Studied
Our data showed that astaxanthin supplementation increases ALT concentrations in adults
Study Details
Access Study
Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.