The efficacy and safety of probiotics in patients with irritable bowel syndrome: Evidence based on 35 randomized controlled trials
Niu HL, Xiao JY
Published in International Journal of Surgery
Key Findings
Across 35 RCTs, probiotics improved global IBS symptoms including abdominal distension/flatulence scores versus placebo, with a favourable safety profile.
Conclusions
Probiotics modestly reduce bloating and flatulence in IBS, though strain effects vary.
Limitations
Marked heterogeneity in strains, doses and outcome scales; several small trials.
Supplements Studied
Randomized controlled trials (RCTs) involving adults with IBS that compared probiotics to placebo or no therapy were eligible for the analysis.
Outcomes Measured
We performed a systematic review and meta-analysis of the efficacy and safety of probiotics in patients with IBS.
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.