case_study
    2017

    Vitamin B1 deficiency in patients with postural tachycardia syndrome (POTS)

    Blitshteyn S

    Published in Neurological Research

    Methodology

    Retrospective review of medical records of 65 consecutive patients with postural tachycardia syndrome evaluated at one clinic, assessing prevalence of vitamin B1 deficiency and response to oral supplementation in deficient patients.

    Key Findings

    A review of records from 65 consecutive patients with postural tachycardia syndrome (mean age 32, range 13-54, 89% female) found vitamin B1 deficiency in 6%. Of the four deficient patients, one experienced significant improvement in symptoms after oral vitamin B1 supplementation. The author concludes that a small subset of these patients may be thiamine deficient and recommends testing and correcting the deficiency.

    Conclusions

    A small subset of patients with POTS may have vitamin B1 deficiency. Testing for vitamin B1 deficiency and correcting the deficiency is recommended.

    Limitations

    A retrospective single-clinic chart review with no control group; only four patients were deficient and only one improved, so this is a preliminary observation rather than evidence that supplementation helps.

    Related Health Concerns

    Study Details

    Year:2017
    Sample Size:65
    Quality Score:3/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.