systematic_review
    2024
    High Quality

    Treatments for Morton's neuroma

    Matthews BG, Thomson CE, Harding MP, McKinley JC, Ware RS

    Published in Cochrane Database of Systematic Reviews

    Abstract

    A Cochrane systematic review assessing the benefits and harms of surgical and non-surgical interventions for Morton's neuroma, an entrapment neuropathy of the interdigital nerve.

    Methodology

    Comprehensive search of Cochrane-standard databases for RCTs and quasi-RCTs of surgical, corticosteroid injection, alcohol sclerosing injection, orthoses, and other conservative treatments for Morton's neuroma.

    Key Findings

    Evidence for most treatments was of low or very low certainty; some short-term pain relief was seen with corticosteroid injection and orthoses, but comparative superiority of any one treatment could not be firmly established.

    Conclusions

    There is insufficient high-quality evidence to strongly recommend one treatment over another for Morton's neuroma; further well-designed RCTs are needed.

    Limitations

    Few high-quality RCTs available; small sample sizes; high risk of bias in most included studies; short follow-up durations.

    Outcomes Measured

    Evidence for most treatments was of low or very low certainty; some short-term pain relief was seen with corticosteroid injection and orthoses, but comparative superiority of any one treatment could not be firmly established.

    Related Health Concerns

    Study Details

    Year:2024
    Quality Score:8/10

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