2000

    The effect of anthocyanins in Vaccinium myrtillus on improving vision under low light conditions

    Nakaishi H, Matsumoto H, Tominaga S, Hirayama M

    Published in Journal of Traditional Medicines

    Abstract

    Double-blind, placebo-controlled crossover study of 15 healthy subjects. Bilberry extract (50mg anthocyanins) significantly improved night vision adaptation and reduced glare recovery time. Effects observed within 2-4 hours and sustained for 8 hours. Mechanism through enhanced rhodopsin regeneration. Traditional use by WWII pilots supported by objective measurements.

    Methodology

    Double-blind, placebo-controlled crossover trial measuring dark adaptation thresholds and glare recovery in healthy volunteers.

    Key Findings

    In a small placebo-controlled crossover study, a single dose of bilberry anthocyanin extract produced a measurable improvement in dark adaptation and reduced glare recovery time compared with placebo, with effects appearing within hours of dosing.

    Conclusions

    Bilberry anthocyanins may transiently aid dark adaptation in healthy eyes, but the effect is small and later, larger trials have generally failed to reproduce night-vision benefits.

    Limitations

    Very small sample, single-dose acute design, non-indexed regional journal, no DOI, and no long-term or clinical vision outcomes.

    Supplements Studied

    In a small placebo-controlled crossover study, a single dose of bilberry anthocyanin extract produced a measurable improvement in dark adaptation and reduced glare recovery time compared with placebo, with effects appearing within hours of dosing.

    In a small placebo-controlled crossover study, a single dose of bilberry anthocyanin extract produced a measurable improvement in dark adaptation and reduced glare recovery time compared with placebo, with effects appearing within hours of dosing.

    Outcomes Measured

    Eye Health Support
    Primary

    Bilberry extract (50mg anthocyanins) significantly improved night vision adaptation and reduced glare recovery time through enhanced rhodopsin regeneration. Effects sustained for 8 hours.

    Study Details

    Year:2000
    Sample Size:15
    Quality Score:3/10

    Access Study

    Original Source

    Disclosures

    Funding

    Not reported; conducted with commercial bilberry extract

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.