rct
    2004

    Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial

    Akhondzadeh S, Fallah-Pour H, Afkham K, Jamshidi AH, Khalighi-Cigaroudi F

    Published in BMC Complementary and Alternative Medicine

    Key Findings

    Saffron 30 mg/day was as effective as imipramine 100 mg/day over six weeks, with fewer anticholinergic side effects.

    Conclusions

    Saffron matched a tricyclic antidepressant in a small pilot trial.

    Limitations

    Pilot size; no placebo arm; single centre.

    Supplements Studied

    Saffron 30 mg/day was as effective as imipramine 100 mg/day over six weeks, with fewer anticholinergic side effects.

    Related Health Concerns

    Depression

    Study Details

    Year:2004
    Sample Size:30
    Duration:6 weeks
    Quality Score:5/10

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