Broccoli or sulforaphane: is it the source or dose that matters?
Yagishita Y, Fahey JW, Dinkova-Kostova AT, Kensler TW
Published in Molecules
Methodology
Review of human intervention studies using broccoli, sprout preparations and purified sulforaphane, comparing bioavailability and dosing.
Key Findings
Bioavailability varies enormously with preparation and myrosinase activity, explaining inconsistent clinical results across trials.
Conclusions
Dose and preparation, not just sulforaphane content, determine clinical effect.
Limitations
Narrative synthesis; no pooled effect estimates.
Supplements Studied
Dose and preparation, not just sulforaphane content, determine clinical effect.
Outcomes Measured
Bioavailability varies enormously with preparation and myrosinase activity, explaining inconsistent clinical results across trials.
Study Details
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