Effects of policosanol on blood lipid profiles: a systematic review and meta-analysis of randomized controlled trials
Gong J, Qin X, Yuan F, Hu M, Chen G, Fang K, Wang D, Jiang S, Li J, Zhao Y, Huang Z, Dong H, Lu F
Published in Nutrition, Metabolism and Cardiovascular Diseases
Methodology
Meta-analysis of 22 randomized controlled trials of policosanol on lipid parameters, with subgroup analysis by study origin
Key Findings
Pooled results favoured policosanol, but effects were confined to trials from Cuba and absent in trials conducted elsewhere
Conclusions
Geographic origin of trials, not biology, explains reported policosanol lipid effects
Limitations
Strong evidence of publication and source bias across the literature
Supplements Studied
Pooled results favoured policosanol, but effects were confined to trials from Cuba and absent in trials conducted elsewhere
Outcomes Measured
Pooled results favoured policosanol, but effects were confined to trials from Cuba and absent in trials conducted elsewhere
Related Health Concerns
Study Details
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