A meta-analysis of inositol for depression and anxiety disorders
Mukai T, Kishi T, Matsuda Y, Iwata N
Published in Human Psychopharmacology: Clinical and Experimental
Methodology
Meta-analysis of randomised placebo-controlled trials of inositol monotherapy or adjunctive therapy in depressive and anxiety disorders.
Key Findings
Inositol was not significantly superior to placebo for depression or anxiety symptom reduction, response or remission rates, although discontinuation rates were similar to placebo.
Conclusions
Current evidence does not support inositol for depressive or anxiety disorders.
Limitations
Few small trials with heterogeneous diagnoses and dosing; underpowered for subgroup effects.
Supplements Studied
Inositol was not significantly superior to placebo for depression or anxiety symptom reduction, response or remission rates.
Outcomes Measured
Inositol was not significantly superior to placebo for depression or anxiety symptoms.
Related Health Concerns
Study Details
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Disclosures
Funding
Academic (Fujita Health University)
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