meta_analysis
    2025
    High Quality

    The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis

    Bulman A, D'Cunha NM, Marx W, Turner M, McKune A, Naumovski N

    Published in Sleep Medicine Reviews

    Methodology

    Systematic review and meta-analysis of 19 randomised controlled trials (18 pooled) of L-theanine supplementation on sleep outcomes across five databases through September 2024

    Key Findings

    L-theanine significantly improved subjective sleep onset latency (SMD 0.15, 95% CI 0.01-0.29), subjective daytime dysfunction (SMD 0.33) and overall subjective sleep quality (SMD 0.43).

    Conclusions

    L-theanine may have a modest role in managing sleep disturbances, particularly subjective sleep onset and quality.

    Limitations

    Effect sizes are small, outcomes are largely subjective, and few trials tested pure L-theanine rather than combination products.

    Supplements Studied

    L-Theanine
    Amino Acid

    L-theanine was shown to significantly improve subjective sleep onset latency (SMD = 0.15, 95 % CI [0.01, 0.29], p = 0.04; n = 10 studies)

    Related Health Concerns

    Study Details

    Year:2025
    Sample Size:897
    Quality Score:8/10

    Disclosures

    Funding

    Not reported

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.