Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis
Wang X, Yang J, Qiu X, Wen Q, Liu M, Zhou D, Chen Q
Published in Nutrients
Methodology
Systematic review and meta-analysis of randomized controlled trials measuring faecal bacterial counts after fructooligosaccharide supplementation.
Key Findings
FOS significantly increased faecal Bifidobacteria and Lactobacilli counts; gastrointestinal side effects such as flatulence and bloating were more common at higher doses.
Conclusions
FOS reliably shifts gut microbiota toward bifidobacteria, with dose-dependent gastrointestinal tolerance limits.
Limitations
Surrogate microbiota endpoints rather than clinical outcomes; heterogeneous doses and analytical methods.
Supplements Studied
FOS supplementation significantly increased the abundance of faecal Bifidobacteria and Lactobacilli in humans.
Outcomes Measured
FOS supplementation significantly increased the abundance of faecal Bifidobacteria and Lactobacilli in humans.
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.