L-citrulline-malate influence over branched chain amino acid utilization during exercise
Sureda A, Cordova A, Ferrer MD, Perez G, Tur JA, Pons A
Published in European Journal of Applied Physiology
Key Findings
Citrulline-malate altered plasma amino acid handling and nitric oxide metabolites after intense cycling, with only modest and inconsistent changes in growth hormone and other hormones.
Conclusions
Citrulline raises arginine availability but does not reliably drive growth hormone secretion.
Limitations
Small athlete-only sample (n=17), acute exercise design, hormonal outcomes secondary.
Supplements Studied
Oral L-citrulline supplementation raises plasma L-arginine concentration and augments NO-dependent signalling.
Outcomes Measured
Oral L-citrulline supplementation raises plasma L-arginine concentration and augments NO-dependent signalling.
Study Details
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