observational
    2015

    Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors

    de Paula LC, Fonseca F, Perazzo F, Cruz FM, Cubero D

    Published in Journal of Alternative and Complementary Medicine

    Methodology

    Prospective single-arm phase II study of 100 mg dry Uncaria tomentosa extract three times daily in 51 patients with advanced solid tumors and no remaining treatment options; EORTC QLQ-C30, FACIT-Fatigue, HADS and Pittsburgh Sleep Quality Index outcomes

    Key Findings

    Treatment was associated with improvement in overall quality of life scores and social functioning in patients with terminal solid tumors, alongside changes in several inflammatory parameters.

    Conclusions

    Cat's claw extract may support quality of life in advanced cancer, but the uncontrolled design prevents causal conclusions.

    Limitations

    Single-arm phase II with no control or placebo group; small sample; subjective endpoints in a palliative population.

    Supplements Studied

    Treatment improved the patients' overall quality of life.

    Related Health Concerns

    Study Details

    Year:2015
    Sample Size:51
    Quality Score:4/10

    Disclosures

    Funding

    Not specified

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.