Effects of Nicotinamide Mononucleotide on Glucose and Lipid Metabolism in Adults: A Systematic Review and Meta-analysis of Randomised Controlled Trials
Chen F, Zhou D, Kong AP, Yim NT
Published in Current Diabetes Reports
Methodology
Systematic review and random-effects meta-analysis of 8 RCTs of NMN 250-2000 mg/day for 14 days to 12 weeks in middle-aged and older adults (49% female, mainly non-diabetic).
Key Findings
No significant benefit of NMN on fasting glucose, fasting insulin, HbA1c, HOMA-IR or lipid profile.
Conclusions
Short-term supplementation of NMN of 250-2000 mg/d did not show significantly positive impacts on glucose control and lipid profile.
Limitations
Small number of RCTs, mainly healthy adults, short durations up to 12 weeks.
Supplements Studied
Short-term supplementation of NMN of 250-2000 mg/d did not show significantly positive impacts on glucose control and lipid profile.
Short-term supplementation of NMN of 250-2000 mg/d did not show significantly positive impacts on glucose control and lipid profile.
Short-term supplementation of NMN of 250-2000 mg/d did not show significantly positive impacts on glucose control and lipid profile.
Outcomes Measured
Short-term supplementation of NMN of 250-2000 mg/d did not show significantly positive impacts on glucose control and lipid profile.
Study Details
Access Study
Disclosures
Funding
Not reported
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