meta_analysis
    2019
    High Quality

    A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA supplementation of bone mineral density in healthy adults

    Unknown authors

    Published in Gynecological Endocrinology

    Key Findings

    DHEA replacement partially increased hip and trochanter BMD in women; no similar effect was observed in men.

    Conclusions

    Raising DHEA levels produces sex-specific skeletal effects, benefiting women more than men.

    Outcomes Measured

    DHEA Enhancement
    Primary

    The results of this meta-analysis suggest that DHEA replacement therapy can partially increase BMD of hip and trochanter in women. Similar results were not observed in men.

    Bone Mineral Density

    DHEA replacement partially increased hip and trochanter BMD in women; no similar effect was observed in men.

    Study Details

    Year:2019
    Quality Score:7/10

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